Pulmonary Allograft Versus Host Disease
نویسندگان
چکیده
A 52-year-old woman underwent bilateral lung transplantation for rheumatoid arthritis–associated interstitial lung disease. Her pretransplant course was notable for immunosuppressive therapy for rheumatoid arthritis with adalimumab, azathioprine, and prednisone. She exhibited extensive pretransplant allosensitization, including 3 low-intensity donorspecific antihuman leukocyte antigen antibodies predicted to react with the allograft, as well as a positive flow cytometric crossmatch at the time of transplant. As a result, her posttransplant induction immunosuppression included rabbit antithymocyte globulin (ATG), plasmapheresis, intravenous (IV) immunoglobulin, and rituximab. Maintenance immunosuppression consisted of tacrolimus, mycophenolate mofetil (MMF), prednisone, and monthly IV immunoglobulin. Antimicrobial
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عنوان ژورنال:
دوره 3 شماره
صفحات -
تاریخ انتشار 2017